Focal cortical lesion detection in multiple sclerosis: 3 tesla DIR versus 7 tesla FLASH-T2*
نویسندگان
چکیده
منابع مشابه
3 Tesla and 7 Tesla MRI of multiple sclerosis cortical lesions.
Cortical lesions are prevalent in multiple sclerosis but are poorly detected using MRI. The double inversion recovery (DIR) sequence is increasingly used to explore the clinical relevance of cortical demyelination. Here we evaluate the agreement between imaging sequences at 3 Tesla (T) and 7T for the presence and appearance of individual multiple sclerosis cortical lesions. Eleven patients with...
متن کاملIncreased cortical grey matter lesion detection in multiple sclerosis with 7 Tesla MRI : a postmortem verification study 2 . 3 7 T postmortem MRI and histopathology study
The relevance of cortical grey matter pathology in multiple sclerosis has become increasingly recognised over the past decade. Unfortunately, a large part of cortical lesions remain undetected on MRI using standard field strength. In vivo studies have shown improved detection by using higher magnetic field strengths up to 7 T. So far, a systematic histopathological verification of ultrahigh-fie...
متن کاملHippocampal T2 hyperintensities on 7 Tesla MRI☆
Hippocampal focal T2 hyperintensities (HT2Hs), also referred to as hippocampal sulcal cavities, are a common finding on Magnetic Resonance (MR) images. There is uncertainty about their etiology and clinical significance. In this study we aimed to describe these HT2Hs in more detail using high resolution 7 Tesla MR imaging, addressing 1) the MR signal characteristics of HT2Hs, 2) their occurrenc...
متن کامل7 Tesla Magnetic Resonance Imaging to Detect Cortical Pathology in Multiple Sclerosis
BACKGROUND Neocortical lesions (NLs) are an important pathological component of multiple sclerosis (MS), but their visualization by magnetic resonance imaging (MRI) remains challenging. OBJECTIVES We aimed at assessing the sensitivity of multi echo gradient echo (ME-GRE) T2*-weighted MRI at 7.0 Tesla in depicting NLs compared to myelin and iron staining. METHODS Samples from two MS patients...
متن کاملDetecting multiple sclerosis cortical lesions post-mortem using 7 Tesla Magnetic Resonance Imaging
Introduction: Although originally considered a white matter (WM) disease, it is now clear that focal cortical grey matter (GM) pathology is an important component of multiple sclerosis (MS). Presently available magnetic resonance imaging (MRI) techniques fail in detecting the actual amount of cortical lesions (CLs). The reason for such a failure is twofold: (i) the small size of CLs relative to...
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ژورنال
عنوان ژورنال: Journal of Magnetic Resonance Imaging
سال: 2011
ISSN: 1053-1807
DOI: 10.1002/jmri.22847